According to Lex Sokolin, DeFi replaces bank hours, forms, and multi-day waits with wallet connections and always-on, on-chain settlement, underscoring a structural advantage for 24/7 trading access and liquidity management. source: Lex Sokolin on X, Ethereum Foundation Traditional banking transfers such as ACH typically require one to three business days and are constrained by branch and processing hours, impacting when traders can fund or withdraw. source: Federal Reserve, NACHA DeFi rails and major DEXs operate continuously, enabling collateral moves, swaps, and perpetuals risk management on weekends and holidays when banks are closed. source: Uniswap Documentation, dYdX Documentation For execution, monitor DEX spot and perp volumes, gas fees, and stablecoin transfer activity during off-hours to assess depth, liquidity, and slippage. source: DeFiLlama, Etherscan